Diffuser refill · Comfort Zone

Comfort Zone Multi-Cat Diffuser Refill 6-Pack 100538644

Six months of multi-cat refills

Updated October 2026

Quick verdict

The value multi-cat refill.

Strength
Six months in one box.
Trade-off
Comfort Zone diffusers only.
Right buyer
Long-term multi-cat use.
Dimensions (seller)
5.63 x 3.69 x 3.56 inches; 13.62 ounces
Product weight
13.6 ounces
Prices change often; the button shows today's price.

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Why it matters

Comfort Zone sells its multi-cat pheromone in 30-day refills; this box has six. They fit Comfort Zone diffusers only, and the maker says the diffuser is reusable for up to 12 months.

Comfort Zone has made calming pheromone products for more than 20 years.

Who it's for, and who should skip it

Good fit if

  • Long-term multi-cat use
  • Comfort Zone diffuser owners
  • Budget-minded buyers

Look elsewhere if

  • Cats with untreated medical problems behind the behavior
  • Owners expecting instant results
  • Outdoor-only cats

Pros and cons

Pros

  • Six 30-day refills
  • Lower cost per month
  • Multi-cat formula

Cons

  • Comfort Zone diffusers only
  • Not FELIWAY-compatible
  • Results vary

Limitations to weigh

  • Sudden spraying, hiding or aggression can be a medical problem; see your vet before relying on a calming product.
  • Plug diffusers into an open outlet in the room your cat uses most, not behind furniture or under a shelf.
  • Give pheromone products a few weeks; most makers say results build over 1-4 weeks.

Specifications

Every figure below comes from the source shown in brackets. Where the maker doesn't state something, we say so instead of estimating.

Product weight13.6 ouncesRetailer
Model number100538644Retailer
WarrantySatisfaction guaranteed. If you’re not satisfied within 90 days, call us at 800-234-2269 so we can make it right. Proof of purchase is required.Retailer
Model nameComfort Zone Multi Cat Calming Diffuser RefillsRetailer
MaterialPlasticRetailer
Pieces6Retailer
In the box6 Comfort Zone MultiCat Diffuser RefillsRetailer
Dimensions (seller)5.63 x 3.69 x 3.56 inches; 13.62 ouncesRetailer

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Final verdict

Stock up here if your Comfort Zone diffuser is already working.

Where to buy

Our links open this exact model's product page. Prices and stock change; check what's included before you order.

Prices change often; the button shows today's price.

Each button opens this exact model. We may earn a commission on tracked links; it never changes what we publish. Disclosure

Questions buyers ask

Does it fit FELIWAY diffusers?
No, Comfort Zone diffusers only.
How long does each refill last?
About 30 days.